Christina Applegate Says She Has 30 Brain Lesions

May 2024 · 2 minute read

In a candid new interview, Christina Applegate gets very real about her daily MS struggle.

Ever since she revealed her diagnosis in 2021, we've been in total awe of how she has handled her journey with MS. From her celebrated appearance at the Emmy's to her honesty on Good Morning America to her fabulous bedazzled walking canes, Applegate has been a beacon of hope and humor.

However, as the Dead to Me and Friends actor revealed on a recent appearance on Dax Shepherd's Armchair Expert podcast, her public display of strength is something of a facade.

"This is the worst thing that's ever happened to me in my entire life," she said on the podcast. "I hate it so much, and I'm so mad about it. You can't overcome it."

She went on to reveal that as a result of the disease, she has developed 30 brain lesions — "sores all over my brain," she says. "My biggest one is behind my right eye, so my right eye hurts a lot."

She explained that in addition to the daily pain caused by the lesions, they are also a constant source of anxiety. "I'm not really happy about all the ones in my brain. If you think that I'm just sitting here with 30 lesions on my brain. It's not a fun one to hang with."

Elsewhere in the podcast, Applegate promoted her own new podcast, MeSsy, which she co-hosts with fellow actor Jami-Lynn Sigler, who was diagnosed with MS two decades ago. As ever, it's clear that Applegate is committed to finding ways to be proactive in the face of her devastating illness.

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